Driver picks the music, shotgun shuts his cake hole.

Dean: I'm not gonna die in a hospital where the nurses aren't even hot.


Dean:I hope your apple pie is freakin’ worth it.


Sam:I miss conversations that didn’t start with 'this killer truck.'


Dean: People believe in Santa Claus. How come I’m not getting hooked up every Christmas?
Sam: Because you’re a bad person.


Dean: Of course, the most troubling question is why do these people assume we're gay?
Sam: Well, you are kind of butch. They probably think you're overcompensating.


Dean: Snow White? I saw that movie. The porn version anyway. There was this wicked Stepmother. Woo, she was wicked.


Dean: I'm gonna go stop the Big Bad Wolf. Which is the weirdest thing I've ever said.


Dean: Can I shoot her?
Sam: Not in public.


Sam and Dean (in unison): Yeah right. Nice guess. It wasn't guess. Right, you're a mind reader. Cut it out Sam. Sam! You think you're being funny but you're being really, really childish. Sam Winchester wears make-up. Sam Winchester cries his way through sex. Sam Winchesters keeps a ruler by the bed and every morning when he wakes up … OK, enough!


Dean: Hey, Ed, listen to me. There's some salt in my duffel. Make a circle and get inside.
Ed: Inside your duffel bag??
Dean: In the salt, you idiot.


Ruby: I wish I could be there, Dean! I wish I could smell the flesh sizzle off your bones. I wish I could be there to hear you scream!
Dean: And I wish you'd shut your pie hole, but we don't always get what we want.


Bobby: You're almost hell's bitch, so you can see hell's other bitches.
Dean: Thank you.


Sam: You know if this doesn't go the way we want, I want you to know that...
Dean: Nooo, no, no, no, no, no.
Sam: No what?
Dean: You're not gonna bust out the misty goodbye speech, okay? I mean, if this is my last day on Earth, I do not want it to be socially awkward.


Dean: That is exactly why our lives suck. I mean, come on, we hunt monsters! What the hell? I mean, normal people, they see a monster, and they run. But not us, no, no, no, we search out things that want to kill us. Or eat us! You know who does that? Crazy people! We are insane! You know, and then there's the bad diner food and then the skeevy motel rooms and then the truck-stop waitress with the bizarre rash. I mean, who wants this life, Sam? Seriously? Do you actually like being stuck in a car with me eight hours a day, every single day? I don't think so! I mean, I drive too fast. And I listen to the same five albums over and over and over again, and I sing along. I'm annoying, I know that. And you, you're gassy! You eat half a burrito, and you get toxic! I mean, you know what? You can forget it. Stay away from me Sam, OK? Because I am done with it. I'm done with the monsters and the hellhounds and the ghost sickness and the damn apocalypse. I'm out. I'm done. Quit.


Sam: She was convinced that he wasn't her real daddy.
Dean: Who was? The plumber, hmmm? A little snaking the pipes??
Sam: Dude, you're confusing reality with porn again.


Bobby: You stupid, stupid son of a bitch. Well, boo-hoo! I am so sorry your feelings are hurt, princess! Are you under the impression that family's supposed to make you feel good, make you an apple pie, maybe? They're supposed to make you miserable! That's why they're family!


Dean: Calm down? I am wearing sunglasses at night! You know who does that? No-talent douchebags! I hate this game! I hate that we're in a procedural cop show, and you want to know why? Because I hate procedural cop shows! There's like three hundred of them on television, they're all the freakin' same.


Walt: Shoot him.
Roy: Shooting Sam was right, but Dean...
Walt: He made us and we just snuffed his brother, idiot. You wanna spend the rest of your life knowing Dean Winchester is on your ass, 'cause I don't. Shoot him.
Dean: Go ahead, Roy. Do it. But I'm gonna warn you -- when I come back, I'm gonna be pissed.


Sam: Dad said they always had the perfect marriage.
Dean: It wasn't perfect until after she died.


Zachariah: Wow. Running from angels... on foot... in Heaven. With out-of-the-box thinking like that, I'm surprised you boys haven't stopped the Apocalypse already.


Dean: I mean we’re supposed to be a team. It’s supposed to be you and me against the world, right?
Sam: Dean, it is!
Dean: (after a moment) Is it?


Zachariah: Didn't we tell you about them? So you know you can't trust them, right? You know Sam and Dean Winchester are psychotically, irrationally, erotically codependent on each other, right?


Dean: Blow me Cas.


Dean: What’s that?
Bobby: That’s the round I mean to put through my skull. Every morning I look at it… I think maybe today is the day I flip the lights out, but I don’t do it. I never do it. You know why? Because I promised you I wouldn’t give up!


Sam: You take care of these guys, okay?
Castiel: That’s not possible
Sam: Then humor me.
Castiel: Oh, I’m supposed to lie. Uh, sure, it’ll be fine...
Sam: Just stop talking.


Lucifer: (to Dean) Dean, even for you this is a whole new mountain of stupid.


Balthazar: You have me confused with the other angel. You know, the one in the dirty trenchcoat who's in love with you?



Dean: Don’t get mad at me. Don’t you do that. I had to. I had to look out for you. That’s my job!
Sam: And what do you think my job is?
Dean: What?
Sam: You save my life, over and over. I mean, you sacrifice everything for me, don’t you think I’d do the same thing for you? You’re my big brother. There’s nothing I wouldn’t do for you. I don’t care what it takes, I’m gonna get you out of this. I guess I gotta save your ass for a change.